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Louis Fries Selected Research

Matrix-M

12/2023The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century.
1/2023Strong CD4+ T-Cell Responses to Ancestral and Variant Spike Proteins Are Established by NVX-CoV2373 Severe Acute Respiratory Syndrome Coronavirus 2 Primary Vaccination.
12/2022Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial.
12/2021Induction of Cross-Reactive Hemagglutination Inhibiting Antibody and Polyfunctional CD4+ T-Cell Responses by a Recombinant Matrix-M-Adjuvanted Hemagglutinin Nanoparticle Influenza Vaccine.
1/2021SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice.
1/2021Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.

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Louis Fries Research Topics

Disease

13Human Influenza (Influenza)
11/2022 - 01/2006
9COVID-19
12/2023 - 12/2020
2Virus Diseases (Viral Diseases)
01/2024 - 01/2021
2Infections
01/2023 - 08/2014
2Malaria
12/2022 - 01/2021
1Asymptomatic Diseases
01/2023
1Hypoxia (Hypoxemia)
01/2023
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2023
1Falciparum Malaria (Plasmodium falciparum Malaria)
01/2021
1Influenza in Birds (Avian Flu)
07/2015
1Anaphylaxis (Anaphylactic Shock)
08/2011
1Injection Site Reaction
06/2011
1Pain (Aches)
06/2011
1Rhinorrhea
01/2006

Drug/Important Bio-Agent (IBA)

21VaccinesIBA
07/2023 - 01/2006
7NVX-CoV2373 adjuvated lipid nanoparticleIBA
12/2023 - 12/2020
7AntigensIBA
01/2021 - 01/2006
6Matrix-MIBA
12/2023 - 01/2021
5Immunoglobulin G (IgG)IBA
01/2024 - 12/2020
5AntibodiesIBA
01/2023 - 01/2006
5Influenza Vaccines (Influenza Vaccine)FDA Link
08/2014 - 01/2006
3Proteins (Proteins, Gene)FDA Link
07/2023 - 01/2021
2Recombinant ProteinsIBA
01/2023 - 01/2023
2AS03 adjuvantIBA
01/2013 - 08/2011
1Messenger RNA (mRNA)IBA
01/2024
1SaponinsIBA
12/2023
1Subunit VaccinesIBA
12/2023
1Biomarkers (Surrogate Marker)IBA
02/2023
1Glycoproteins (Glycoprotein)IBA
01/2023
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
01/2023
1Nucleocapsid ProteinsIBA
01/2023
1Neutralizing AntibodiesIBA
01/2023
1Rabies Vaccines (Rabies Vaccine)FDA Link
12/2022
1rabivaxIBA
12/2022
1asparaginyl-prolineIBA
01/2021
1NanovaccinesIBA
01/2018
1EpitopesIBA
07/2015
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
08/2014
1Bacterial Outer Membrane ProteinsIBA
03/2011
1Detergents (Detergent)IBA
03/2011
1fluarixIBA
11/2008
1FluLavalIBA
11/2008
1Membrane Proteins (Integral Membrane Proteins)IBA
03/2006
1Secretory Immunoglobulin A (SIgA)IBA
01/2006

Therapy/Procedure

1Intranasal Administration
01/2006